منابع مشابه
RecA family proteins in archaea: RadA and its cousins.
Recombinases of the RecA family are essential for homologous recombination and underpin genome stability, by promoting the repair of double-stranded DNA breaks and the rescue of collapsed DNA replication forks. Until now, our understanding of homologous recombination has relied on studies of bacterial and eukaryotic model organisms. Archaea provide new opportunities to study how recombination o...
متن کاملWidespread Disulfide Bonding in Proteins from Thermophilic Archaea
Disulfide bonds are generally not used to stabilize proteins in the cytosolic compartments of bacteria or eukaryotic cells, owing to the chemically reducing nature of those environments. In contrast, certain thermophilic archaea use disulfide bonding as a major mechanism for protein stabilization. Here, we provide a current survey of completely sequenced genomes, applying computational methods ...
متن کاملFibrillarin-like proteins occur in the domain Archaea.
Fibrillarin is found in the nucleolus of Eucarya and associated with small nucleolar RNAs. It is involved in the processing of precursor rRNA. Two genes, encoding fibrillarin-like proteins from Methanococcus voltae and Methanococcus vannielii, have been isolated. The genes were named flpA (fibrillarin-like protein).
متن کاملA Systematic Survey of Mini-Proteins in Bacteria and Archaea
BACKGROUND Mini-proteins, defined as polypeptides containing no more than 100 amino acids, are ubiquitous in prokaryotes and eukaryotes. They play significant roles in various biological processes, and their regulatory functions gradually attract the attentions of scientists. However, the functions of the majority of mini-proteins are still largely unknown due to the constraints of experimental...
متن کاملArchaea and the Origin(s) of DNA Replication Proteins
The deepest phylogenetic division in the universal tree (vertical line in Figure 1) is that separating bacteria from the clade comprising archaea and eukaryotes. The prokaryote–eukaryote split (horizontal line in Figure 1), originally delineated on the basis of differences between (eu)bacterial and eukaryotic cellular ultrastructure, is a phenetic dichotomy (see Doolittle, 1996, and references ...
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ژورنال
عنوان ژورنال: Trends in Biochemical Sciences
سال: 2010
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2010.03.003